Research & Publications

Advancing cerebrovascular neurosurgery through clinical research and academic scholarship

161+
Peer-Reviewed Publications
6,670+
Citations
14
Book Chapters
42
H-Index

Active Clinical Trials

Participating in multicenter clinical trials to advance evidence-based treatment for cerebrovascular disease.

Actively Enrolling

ASPIRE Trial

Anticoagulation for Stroke Prevention and Recovery After Intracerebral Hemorrhage

The ASPIRE trial is a Phase III, randomized, double-blinded, multicenter clinical trial evaluating the efficacy and safety of anticoagulation compared with aspirin in patients with recent intracerebral hemorrhage and atrial fibrillation. The trial aims to determine whether apixaban is superior to aspirin for prevention of the composite outcome of any stroke or death from any cause.

Role
Site Principal Investigator
Phase
Phase III
Design
Randomized, Double-Blinded
Enrollment
700 Patients (Multicenter)

Research Interests

My research focuses on advancing the understanding and treatment of cerebrovascular disease through both basic science and clinical investigation.

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Brain Aneurysm Treatment

Flow diversion techniques, intrasaccular flow disruption devices, and endovascular approaches for complex cerebral aneurysms.

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Cerebrovascular Genetics

Investigating the genetic and molecular basis of vascular malformations, including AVMs and moyamoya disease.

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Stroke & Neuroprotection

Neuroprotective strategies for ischemic stroke, brain edema management, and cerebral ischemia outcomes research.

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Stereotactic Radiosurgery

Proton beam and photon-based radiosurgery for cerebral AVMs, brain tumors, and functional neurological disorders.

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Brain Vascular Mapping

Single-cell atlas of the human brain vasculature and detailed mapping of cerebrovascular anatomy.

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Medical Device Innovation

Development and evaluation of neurovascular devices including flow diverters and surgical robotics.

Selected Publications

Representative peer-reviewed publications from a body of work spanning brain aneurysms, stroke, vascular malformations, and neurosurgical innovation.

JAMA Neurology
Intrasaccular Flow Disruption for Treatment of Intracranial Aneurysms — A Review
Walcott BP
Science
A Single-Cell Atlas of the Normal and Malformed Human Brain Vasculature
Winkler EA, Kim CN, Ross JM, ... Walcott BP, ... Nowakowski TJ — Science, 2022
JAMA Surgery
Flow Diversion for the Treatment of Intracranial Aneurysms
Walcott BP, Stapleton CJ, Choudhri OA, Patel AB — JAMA Surgery, 2016
Operative Neurosurgery
The Path to Surgical Robotics in Neurosurgery
Walcott BP, Spetzler RF, Chang SD, Muacevic A, Moll F — Operative Neurosurgery, 2021
Neurosurgery
Proton Beam Stereotactic Radiosurgery for Pediatric Cerebral Arteriovenous Malformations
Walcott BP, Hattangadi-Gluth JA, Stapleton CJ, Ogilvy CS, Chapman PH, Loeffler JS — Neurosurgery, 2014
J Cereb Blood Flow Metab
BMP Signaling Modulation Attenuates Cerebral Arteriovenous Malformation Formation in a Vertebrate Model
Walcott BP — Journal of Cerebral Blood Flow and Metabolism, 2014
Neurosurgical Focus
Effect of Glibenclamide on the Prevention of Secondary Brain Injury Following Ischemic Stroke in Humans
Khanna A, Walcott BP, Kahle KT, Simard JM — Neurosurgical Focus, 2014

View All Publications on PubMed →

Peer Review

Serving as a peer reviewer for leading medical and neurosurgical journals, evaluating cutting-edge research to advance the field.

The Lancet Neurology JAMA Surgery Neurosurgery Journal of Neurosurgery Operative Neurosurgery Neurosurgical Focus American Journal of Human Genetics J Cerebral Blood Flow & Metabolism

Research Funding

Research funded by nationally recognized organizations supporting advances in cerebrovascular neurosurgery.

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National Institutes of Health (NIH)

Research Funding — Cerebrovascular Disease

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Brain Aneurysm Foundation

Research Grant — Vascular Malformation Genomics

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Congress of Neurological Surgeons

Christopher C. Getch, MD Fellowship (2014–2016)

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